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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Issue: June 2024

Volume 9 | Issue 6

Impact factor: 8.15

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Paper Title: Preparation of hollow microspere loaded with Anti-Infective drug (Cefexime)
Authors Name: Dighe Jaideep Appasaheb , Dighe Vishal Bhausaheb , Nirmal Tejal
Unique Id: IJSDR2405024
Published In: Volume 9 Issue 5, May-2024
Abstract: In the present study an attempt was made to prepare Hollow Microspheres loaded with an Anti-Infective Drug. Cefixime is a third- generation cephalosporin antibiotic which is highly effective against various infections. Different formulations were prepared by Emulsion Solvent Diffusion method. FTIR and DSC studies confirme¬¬d that there was no interaction between drug and the polymers. Particle size for all formulations were within the range of 560-570 nm respectively. The images from SEM revealed that the particles were spherical in shape. The drug entrapment efficiency of formulations was found to be in the range of 89.34%. Thus, the prepared Hollow Microspheres proved to maintain the therapeutic index over a continued period of time and be a potential candidate as a sustained drug delivery system.
Keywords: Cefixime, Hollow Microspheres, Sustained Drug Delivery, Invitro drug release, Pharmacokinetics.
Cite Article: "Preparation of hollow microspere loaded with Anti-Infective drug (Cefexime)", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 5, page no.184 - 190, May-2024, Available :http://www.ijsdr.org/papers/IJSDR2405024.pdf
Downloads: 000342234
Publication Details: Published Paper ID: IJSDR2405024
Registration ID:211201
Published In: Volume 9 Issue 5, May-2024
DOI (Digital Object Identifier):
Page No: 184 - 190
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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