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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15

Issue: June 2024

Volume 9 | Issue 6

Impact factor: 8.15

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Paper Title: A Review on Bilayer tablet for Hypertension and Diabetes
Authors Name: Nilesh P. Musmade , Rahul S. Kamble , Dr. V.M. Satpute , Ghodke S.R. , Navgire Pravin
Unique Id: IJSDR2405036
Published In: Volume 9 Issue 5, May-2024
Abstract: The bilayer tablet is a new technology for a successful improvement of controlled release method alongside numerous functions to ensure successful drug transport. Bilayer drugs encompass layers, which are a gradual-release layer and an instantaneous-release layer. In addition to stepped forward positive technology to overcome the shortcomings of single-layer tablet. Bi-layer tablet formulations have been required due to separate collectively incompatible lively pharmaceutical ingredients (APIs). The bilayer tablet cloth consists of both compressibility and consolidation. The cutting-edge paintings specialize in the development of a double-layer pill of empagliflozin and aliskiren inside the treatment of diabetes and hypertension. The release of aliskiren and empagliflozin was controlled with the aid of their method into a right way and sustained release layer. both layers had been prepared by moist granulation. The compatibility of polymers and excipients in conjunction with natural drugs became evaluated the use of FTIR research. tablets had been prepared and parameters earlier than and after compression, in vitro dissolution trying out, launch rate kinetics and stability studies had been evaluated. The feet-IR spectrum confirms the absence of chemical interplay among the drug and the polymers. The parameters before and after compression have been observed to be within perfect limits. For the bilayer tablet, one system of each layer changed into decided on based totally on the in vitro dissolution profile records. The cause for this constant mixture is the joint administration of drugs with extraordinary mechanisms of movement, a reduction in dosing frequency and a boom in patient compliance.
Keywords: Hypertension, Diabetes, Bilayer Tablet, Compression, Consolidation.
Cite Article: "A Review on Bilayer tablet for Hypertension and Diabetes", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 5, page no.279 - 283, May-2024, Available :http://www.ijsdr.org/papers/IJSDR2405036.pdf
Downloads: 000342048
Publication Details: Published Paper ID: IJSDR2405036
Registration ID:211193
Published In: Volume 9 Issue 5, May-2024
DOI (Digital Object Identifier):
Page No: 279 - 283
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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